PLUNC rabbit pAb

This gene is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The encoded antimicrobial protein displays antibacterial activity against Gram-negative bacteria. It is thought to be involved in inflammatory responses to irritants in the upper airways and may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. Multiple transcript variants resulting from alternative splicing in the 3' UTR have been detected, but the full-length nature of only three are known. [provided by RefSeq, Aug 2014],

Product Specifications

Background

UniProt

Q9NP55

Swiss Prot

Q9NP55

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from the Internal region of human PLUNC.

Clonality

Polyclonal

Source

Rabbit

Applications

IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 , Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Storage Conditions

-20°C/1 year

Fragment

IgG

Subcellular Location

Secreted . Apical side of airway epithelial cells. Detected in airway surface liquid, nasal mucus and sputum.

Other Product Names

BPIFA1; LUNX; NASG; PLUNC; SPURT; BPI fold-containing family A member 1; Lung-specific protein X; Nasopharyngeal carcinoma-related protein; Palate lung and nasal epithelium clone protein; Secretory protein in upper respiratory tracts; Trach