CD32 (phospho Tyr292) rabbit pAb
The Fc fragment of IgG receptor IIb encoded by FCGR2B is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.
Product Specifications
Background
Synonyms
Gene ID
2213
UniProt
P31994
Cellular Locus
Cell membrane; Single-pass type I membrane protein.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human CD32 around the phosphorylation site of Tyr292. AA range:258-307
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
32kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES5227-1.pdf
Observed Molecular Weight
32 kD
Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Other Product Names
Gene ID (Human)
2213
SwissProt (Human)
P31994
Available Sizes
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