Naspm
Product Specifications
Product Name Alternative
1-Naphthylacetyl spermine
UNSPSC Description
Naspm (1-Naphthyl acetyl spermine), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist.
Target Antigen
iGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Naspm.html
Purity
96.30
Solubility
DMSO : 10 mg/mL (ultrasonic)
Smiles
O=C(NCCCNCCCCNCCCN)CC1=C2C=CC=CC2=CC=C1
Molecular Weight
370.53
References & Citations
[1]Koike M, et al. Blocking effect of 1-naphthyl acetyl spermine on Ca2+-permeable AMPA receptors in cultured rat hippocampal neurons. Neurosci Res. 1997 Sep;29(1):27-36.Cell Rep. 2023 Dec 3;42(12):113551.|iScience. 2023 Mar.|J Headache Pain. 2022 Aug 10;23(1):98.|Neurobiol Dis. 2024 Mar 8:106471.|Neuroscience. 2021 Sep 9;S0306-4522(21)00454-1.|Toxicol In Vitro. 2017 Oct;44:57-65. |Cell Rep. 2020 Nov 10;33(6):108369.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-12506/Naspm-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-12506/Naspm-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
122306-11-0
Available Sizes
Curated Selection
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