CENP-A (phospho Ser7) rabbit pAb
Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. This gene encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. The protein is a replication-independent histone that is a member of the histone H3 family. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2015],
Product Specifications
Background
Synonyms
CENPA; Histone H3-like centromeric protein A; Centromere autoantigen A; Centromere protein A; CENP-A
Gene ID
1058
UniProt
P49450
Cellular Locus
Host
Rabbit
Species Reactivity
Human,Rat,Mouse,
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human Centromeric Protein A around the phosphorylation site of Ser7. AA range:1-50
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
IF, ELISA
Validated Applications
IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES4510-1.pdf
Subcellular Location
Other Product Names
CENPA; Histone H3-like centromeric protein A; Centromere autoantigen A; Centromere protein A; CENP-A
Gene ID (Human)
1058
SwissProt (Human)
P49450
Available Sizes
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