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G-CSFR rabbit pAb

The protein encoded by this gene is the receptor for colony stimulating factor 3, a Cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of Cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. [provided by RefSeq, Aug 2010],

Product Specifications

Background

The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. [provided by RefSeq, Aug 2010]

Synonyms

CSF3R; GCSFR; Granulocyte colony-stimulating factor receptor; G-CSF receptor; G-CSF-R; CD114

Gene ID

1441

UniProt

Q99062

Cellular Locus

[Isoform 2]: Secreted.; Cell membrane ; Single-pass type I membrane protein.

Host

Rabbit

Species Reactivity

Human,Rat,Mouse,

Reactivity

Human; Rat; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human CSF3R. AA range:321-370

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, ELISA

Validated Applications

WB,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight

92kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES4257-1.pdf

Observed Molecular Weight

92 kD

Subcellular Location

[Isoform 2]: Secreted .; Cell membrane ; Single-pass type I membrane protein .

Other Product Names

CSF3R; GCSFR; Granulocyte colony-stimulating factor receptor; G-CSF receptor; G-CSF-R; CD114

Gene ID (Human)

1441

SwissProt (Human)

Q99062

Available Sizes

Curated Selection

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