ZFYVE19 rabbit pAb

Disease: A chromosomal aberration involving ZFYVE19 is associated with acute myeloblastic leukemia (AML). Translocation t (11;15) (q23;q14) with MLL/HRX. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Contains 1 FYVE-type zinc finger. tissue specificity: Detected in brain, heart, skeletal muscle, kidney and liver.

Product Specifications

Background

Disease:A chromosomal aberration involving ZFYVE19 is associated with acute myeloblastic leukemia (AML) . Translocation t (11;15) (q23; q14) with MLL/HRX., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Contains 1 FYVE-type zinc finger., tissue specificity:Detected in brain, heart, skeletal muscle, kidney and liver.

UniProt

Q96K21

Swiss Prot

Q96K21

Reactivity

Human; Rat; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human ZFYVE19. AA range:311-360

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Molecular Weight

50kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

50kD

Fragment

IgG

Subcellular Location

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cleavage furrow . Midbody, Midbody ring . Localizes mainly on centrosomes in interphase and early mitosis. Localizes at the cleavage furrow and midbody ring in late mitosis and cytokinesis. .