PIN1 Mouse Monoclonal Antibody [Clone ID: LBI4H1]
Product Specifications
Background
Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2011]
Synonyms
DOD; UBL5
Gene Name
Peptidylprolyl cis/trans isomerase, NIMA-interacting 1
Gene ID
5300
UniProt
Q13526
Conjugation
Unconjugated
Related Pathways
RIG-I-like receptor signaling pathway
Field of Research
RIG-I-like receptor signaling pathway
Concentration
1 mg/ml
Dilution
WB 1:500
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
PIN1
Overview
PIN1 mouse monoclonal antibody, clone LBI4H1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=5300
Uniprot URL
https://www.uniprot.org/uniprot/Q13526
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