Rab 3 GAP p130 rabbit pAb

This gene encodes the catalytic subunit of a Rab GTPase activating protein. The encoded protein forms a heterodimer with a non-catalytic subunit to specifically regulate the activity of members of the Rab3 subfamily of small G proteins. This protein mediates the hydrolysis of GTP bound Rab3 to the GDP bound form. Mutations in this gene are associated with Warburg micro syndrome. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010],

Product Specifications

Background

UniProt

Q15042

Swiss Prot

Q15042

Reactivity

Human; Rat; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human RAB3GAP1. AA range:538-587

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Molecular Weight

117kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

117kD

Fragment

IgG

Subcellular Location

Cytoplasm . In neurons, it is enriched in the synaptic soluble fraction.

Other Product Names

RAB3GAP1; KIAA0066; RAB3GAP; Rab3 GTPase-activating protein catalytic subunit; RAB3 GTPase-activating protein 130 kDa subunit; Rab3-GAP p130; Rab3-GAP