Maspin rabbit pAb

Function: Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. similarity: Belongs to the serpin family. Ov-serpin subfamily. tissue specificity: Normal mammary epithelial cells.

Product Specifications

Background

Function:Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity., similarity:Belongs to the serpin family. Ov-serpin subfamily., tissue specificity:Normal mammary epithelial cells.

Synonyms

SERPINB5; PI5; Serpin B5; Maspin; Peptidase inhibitor 5; PI-5

Gene ID

5268

UniProt

P36952

Cellular Locus

Secreted, extracellular space.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human Serpin B5. AA range:91-140

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, IHC, IF, ELISA

Validated Applications

WB,IHC,IF,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight

40kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES2748-1.pdf

Observed Molecular Weight

40 kD

Subcellular Location