HSP105 rabbit pAb

Function: Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities. PTM: Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity. similarity: Belongs to the heat shock protein 70 family. subunit: Interacts with HSPA8/HSC70. tissue specificity: Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.

Product Specifications

Background

Function:Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities., PTM:Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity., similarity:Belongs to the heat shock protein 70 family., subunit:Interacts with HSPA8/HSC70., tissue specificity:Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.

Product Name Alternative

HSPH1; HSP105; HSP110; KIAA0201; Heat shock protein 105 kDa; Antigen NY-CO-25; Heat shock 110 kDa protein

UniProt

Q92598

Swiss Prot

Q92598

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human HSP105. AA range:791-840

Target

HSP105

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.