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CTPS rabbit pAb

This gene encodes an enzyme responsible for the catalytic conversion of UTP (uridine triphosphate) to CTP (cytidine triphospate). This reaction is an important step in the biosynthesis of phospholipids and nucleic acids. Activity of this proten is important in the immune system, and loss of function of this gene has been associated with immunodeficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],

Product Specifications

Background

This gene encodes an enzyme responsible for the catalytic conversion of UTP (uridine triphosphate) to CTP (cytidine triphospate) . This reaction is an important step in the biosynthesis of phospholipids and nucleic acids. Activity of this proten is important in the immune system, and loss of function of this gene has been associated with immunodeficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

Synonyms

CTPS1; CTPS; CTP synthase 1; CTP synthetase 1; UTP--ammonia ligase 1

Gene ID

1503

UniProt

P17812

Cellular Locus

Cytoplasm, cytosol. Mainly cytosolic but when active detected in long filamentous structures (PubMed:25223282). Co-localizes with TNK2 in the cytosolic filaments (By similarity)..

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human CTPS. AA range:60-109

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, IHC, IF, ELISA

Validated Applications

WB,IHC,IF,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Molecular Weight

67kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES2070-1.pdf

Observed Molecular Weight

67 kD

Subcellular Location

Cytoplasm, cytosol . Mainly cytosolic but when active detected in long filamentous structures (PubMed:25223282) . Co-localizes with TNK2 in the cytosolic filaments (By similarity) . .

Other Product Names

CTPS1; CTPS; CTP synthase 1; CTP synthetase 1; UTP--ammonia ligase 1

Gene ID (Human)

1503

SwissProt (Human)

P17812

Available Sizes

Curated Selection

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