P53 (Mono Methyl Lys370) Mouse mAb
P53 plays a major role in the cellular response to DNA damage and other genomic aberrations. The activation of p53 can lead to either cell cycle arrest and DNA repair, or apoptosis. p53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro.
Product Specifications
Background
Product Name Alternative
Cellular tumor antigen p53 antibody, Cys 51 stop antibody, Tp53 antibody, Tumor protein p53 antibody
UniProt
P04637
Swiss Prot
P04637
Reactivity
Human, Rat, Mouse
Immunogen
Synthetic Peptide
Clonality
Monoclonal
Source
Mouse
Applications
IHC
Concentration
1mg/mL
Dilution
IHC 1;500-1,000
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Molecular Weight
53kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
53kDa
Fragment
IgG1
Subcellular Location
Cytoplasm, Cytoplasm. Nucleus
Other Product Names
Cellular tumor antigen p53 antibody, Cys 51 stop antibody, Tp53 antibody, Tumor protein p53 antibody
Gene ID (Human)
7157
Available Sizes
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