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CD20 Mouse mAb

CD20 is a non glycosylated protein with a molecular weight of 35 or 37 kDa depending on the degree of phosphorylation. Although not a member of the tetraspanin superfamily of cell surface receptors, it crosses the cell membrane four times. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca2+ channel subunit.

Product Specifications

Background

CD20 is a non glycosylated protein with a molecular weight of 35 or 37 kDa depending on the degree of phosphorylation. Although not a member of the tetraspanin superfamily of cell surface receptors, it crosses the cell membrane four times. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca2+ channel subunit.

Synonyms

B lymphocyte antigen CD20, B1, Bp35, LEU 16, MS4A1, MS4A1, MS4A2, S7

Gene ID

931

UniProt

P11836

Cellular Locus

Membrane

Host

Mouse

Species Reactivity

Human,Rat,Mouse

Reactivity

Human, Rat, Mouse

Immunogen

Synthetic Peptide

Clonality

Monoclonal

Isotype

IgG1

Source

Mouse

Applications

IHC

Validated Applications

IHC

Stability

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Concentration

1 mg/mL

Dilution

IHC 1:200

Molecular Weight

35-37kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/mAb/EM1048-1.pdf

Observed Molecular Weight

35 - 37 kDa

Subcellular Location

Membrane

Other Product Names

B lymphocyte antigen CD20, B1, Bp35, LEU 16, MS4A1, MS4A1, MS4A2, S7

Gene ID (Human)

931

SwissProt (Human)

P11836

Available Sizes

Curated Selection

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