Citropten
Citropten (5, 7-dimethoxycoumarin) is one of the coumarin derivatives. Citropten is an effective oral anticancer agent. Citropten has anti-proliferative activity against A2058 and B16 melanoma cells. Citropten exerts anti-inflammatory effects through the NFκB and MAPK signaling pathways. Citropten acts as an antidepressant through heat shock protein-70, monoamine oxidase-A and inhibition of apoptosis[1] [2] [3].
Product Specifications
CAS Number
487-06-9
Product Name Alternative
5,7-Dimethoxycoumarin; Limettin
UNSPSC
12352005
Hazard Statement
H302
Target
ERK; JNK; p38 MAPK
Type
Natural Products
Related Pathways
MAPK/ERK Pathway; Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/citropten.html
Purity
99.41
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1OC2=C(C(OC)=CC(OC)=C2)C=C1
Molecular Formula
C11H10O4
Molecular Weight
206.20
Precautions
H302
References & Citations
Citrusaurantifolia
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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