L-Pyroglutamyl-L-prolyl-L-valine p-nitroanilide

<b>Catalog number: </b>MDP0273_x000D_ <b>Name:</b> L-Pyroglutamyl-L-prolyl-L-valine p-nitroanilide_x000D_ <b>Other name(s): </b>Pyr-Pro-Val-pNA_x000D_ <b>Molecular Formula: </b>C₂₁H₂₇N₅O₆_x000D_ <b>Molecular Mass: </b>445.47_x000D_ <b>CAS #: </b>83329-36-6_x000D_ <b>Storage Temperature: </b>-20C_x000D_ <b>Indication for Use:</b>_x000D_ This product if for Research Use Only (RUO). This product is not for administration to humans or animals. This product is not for human or veterinary diagnostic or therapeutic use._x000D_ _x000D_ <b>Safety:</b>_x000D_ User must review the Safety Data Sheet (SDS) provided with this product. In addition, this product should not be ingested, inhaled, swallowed or put in contact with eyes, skin or clothes._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Tanaka H, Shimazu T, Sugimoto H, Yoshioka T, Sugimoto T. A sensitive and specific assay for granulocyte elastase in inflammatory tissue fluid using L-pyroglutamyl-L-prolyl-L-valine-p-nitroanilide Clin Chim Acta. 1990 Feb 28;187(2):173-80._x000D_ 2: Filippova IYu, Lysogorskaya EN, Oksenoit ES, Rudenskaya GN, Stepanov VM. L-Pyroglutamyl-L-phenylalanyl-L-leucine-p-nitroanilide--a chromogenic substrate for thiol proteinase assay Anal Biochem. 1984 Dec;143(2):293-7._x000D_ 3: Hayakawa T, Naruse S, Kitagawa M, Kondo T. [Elastase] Nihon Rinsho. 1995 May;53(5):1192-7._x000D_ 4: Abe K, Watanabe N, Kosaka T, Yamada M, Tokui T, Ikeda T. Hydrolysis of synthetic substrate, L-pyroglutamyl p-nitroanilide is catalyzed solely by pyroglutamyl aminopeptidase I in rat liver cytosol Biol Pharm Bull. 2003 Nov;26(11):1528-33._x000D_ 5: Abuin E, Lissi E, Ahumada M, Calder√≥n C. Effect of human serum albumin on the kinetics of N-glutaryl-L-phenylalanine p-nitroanilide hydrolysis catalyzed by Œ±-chymotrypsin Protein J. 2011 Feb;30(2):143-7._x000D_ 6: Kramps JA, van Twisk C, van der Linden AC. L-Pyroglutamyl-L-prolyl-L-valine-p-nitroanilide, a highly specific substrate for granulocyte elastase Scand J Clin Lab Invest. 1983 Sep;43(5):427-32._x000D_ 7: Abuin E, Lissi E, Duarte R. Kinetics of N-glutaryl-L-phenylalanine p-nitroanilide hydrolysis catalyzed by alpha-chymotrypsin in aqueous solutions of dodecyltrimethylammonium bromide J Colloid Interface Sci. 2005 Mar 15;283(2):539-43._x000D_ 8: Malthouse JPG. Correction to Kinetic Study of the Effect of pH on the Trypsin-Catalyzed Hydrolysis of N-Œ±-benzyloxycarbonyl-l-lysine-p-nitroanilide: Mechanism of Trypsin Catalysis ACS Omega. 2020 May 26;5(22):13462._x000D_ 9: Sharma SK, Castellino FJ. The chemical synthesis of the chromogenic substrates, H-D-Val-L-Leu-L-Lys-p-nitroanilide (S2251) and H-D-Ile-L-Pro-L-ARG-p-nitroanilide (S2288) Thromb Res. 1990 Jan 1;57(1):127-38._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/32201777">10: Malthouse JPG. Kinetic Studies of the Effect of pH on the Trypsin-Catalyzed Hydrolysis of N-Œ±-benzyloxycarbonyl-l-lysine-p-nitroanilide: Mechanism of Trypsin Catalysis ACS Omega. 2020 Mar 3;5(10):4915-4923. </a>_x000D_ _x000D_ <strong>Products Related to L-Pyroglutamyl-L-prolyl-L-valine p-nitroanilide</strong>: <a href="https://moleculardepot.com/product-category/peptides/">Peptides</a>