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HKI 357

irreversible inhibitor of ErbB2 (HER2) and EGFR

Product Specifications

CAS Number

848133-17-5

Product Name Alternative

(E)-N-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide

Field of Research

Tyrosine Kinase EGFR

Purity

0.98

Form

Off-white solid

Solubility

Soluble in DMSO

Smiles

ClC1=CC(NC(C2=C3)=C(C#N)C=NC2=CC(OCC)=C3NC(/C=C/CN(C)C)=O)=CC=C1OCC4=CC=CC(F)=C4

Molecular Formula

C31H29ClFN5O3

Molecular Weight

574.05

Shipping Conditions

Blue ice

Storage Conditions

Store at -20°C.

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