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SGC-CK1γ-1

SGC-CK1γ-1 is a potent and selective probe for the CK1γ subfamily. SGC-CK1γ-1 can inhibit LRP6 phosphorylation levels. SGC-CK1γ-1 can selectively inhibit the CK1γ kinases in living cells and inhibit both WNT signaling and human cytomegalovirus (CMV) replication. SGC-CK1γ-1 can be used for the research of infection[1].

Product Specifications

UNSPSC

12352005

Target

CMV; LDLR; Wnt

Related Pathways

Anti-infection; Metabolic Enzyme/Protease; Stem Cell/Wnt

Field of Research

Infection

Smiles

N#CC1=CC=C2C(N=C(NC3=CC=C(N4CCOCC4)C(Cl)=C3)N2)=C1

Molecular Formula

C18H16ClN5O

Molecular Weight

353.81

References & Citations

[1]Capener JL, et al. Development of a chemical probe to enable characterization of the casein kinase 1γ subfamily. bioRxiv [Preprint]. 2025 Sep 16:2025.09.10.675406.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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