Golvatinib (E7050)

928037-13-2

1-N'-[2-fluoro-4-[2-[[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]amino]pyridin-4-yl]oxyphenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide

Tyrosine Kinase c-MET

0.98

A solid

insoluble in H2O; ≥1.39 mg/mL in EtOH with ultrasonic; ≥15.85 mg/mL in DMSO with gentle warming

CN1CCN(CC1)C2CCN(CC2)C(=O)NC3=NC=CC(=C3)OC4=CC(=C(C=C4)NC(=O)C5(CC5)C(=O)NC6=CC=C(C=C6)F)F

C33H37F2N7O4

633.69

Blue ice

Store at -20°C.