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(Rac) -PD0299685

(Rac) -PD0299685 is a Ca (2+) channel α2δ ligand that was investigated for relieving interstitial cystitis pain in a randomized, double-blind, placebo-controlled phase IIa study. (Rac) -PD0299685 demonstrated a clinically significant reduction in daily worst pain severity scores at the 60 mg dose compared to placebo. (Rac) -PD0299685 is also a potent voltage-dependent calcium channel inhibitor for the study of retina-related diseases.

Product Specifications

CAS Number

[313651-02-4]

UNSPSC

12352211

Target

Calcium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/rac-pd0299685.html

Smiles

O=C(CC(CC(CCC)C)CN)O

Molecular Formula

C10H21NO2

Molecular Weight

187.28

References & Citations

[1]Investigation of a Ca2+ channel α2δ ligand for the treatment of interstitial cystitis: results of a randomized, double-blind, placebo controlled phase II trial

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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