XVA143
Product Specifications
CAS Number
264275-77-6
Target
Integrin
Related Pathways
Cytoskeletal Signaling
Bioactivity
XVA143 is an integrin ?/? I-like allosteric antagonist that inhibits LFA-1 (?L?2 integrin) -dependent firm adhesion and induces an extended conformation of integrins.
Smiles
C(NCC1=CC(O)=CC=C1)(=O)C2=CC(Cl)=C(C(N[C@@H](CNC(=O)C3=CC(O)=CC(O)=C3)C(O)=O)=O)C(Cl)=C2
Molecular Formula
C25H21Cl2N3O8
Molecular Weight
562.36
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Curated Selection
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