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EPZ5676

DOT1L inhibitor,potent and SAM competitive

Product Specifications

Product Name Alternative

(2R,3S,4S,5R)-2-(6-aminopurin-9-yl)-5-[[[3-[2-(6-tert-butyl-1H-benzimidazol-2-yl)ethyl]cyclobutyl]-propan-2-ylamino]methyl]oxolane-3,4-diol

Field of Research

Chromatin Epigenetics Histone Methyltransferase

Purity

0.98

Form

A solid

Solubility

≥28.15 mg/mL in DMSO; insoluble in H2O; ≥50.3 mg/mL in EtOH with ultrasonic

Smiles

CC(C)N(CC1C(C(C(O1)N2C=NC3=C2N=CN=C3N)O)O)C4CC(C4)CCC5=NC6=C(N5)C=C(C=C6)C(C)(C)C

Molecular Formula

C30H42N8O3

Molecular Weight

562.71

Shipping Conditions

Blue ice

Storage Conditions

Store at -20°C.

CAS Number

1380288-87-8

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