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Cobimetinib

Selective MEK inhibitor

Product Specifications

Product Name Alternative

[3,4-difluoro-2-(2-fluoro-4-iodoanilino)phenyl]-[3-hydroxy-3-[(2S)-piperidin-2-yl]azetidin-1-yl]methanone

Sequence

GDC-0973;XL-518;GDC 0973;XL 518;GDC0973;XL518

Field of Research

MAPK Signaling MEK1 2

Purity

0.9971

Solubility

≥26.55 mg/mL in DMSO; insoluble in H2O; ≥33.53 mg/mL in EtOH with gentle warming

Smiles

C1CCNC(C1)C2(CN(C2)C(=O)C3=C(C(=C(C=C3)F)F)NC4=C(C=C(C=C4)I)F)O

Molecular Formula

C21H21F3IN3O2

Molecular Weight

531.31

Shipping Conditions

Blue ice

Storage Conditions

Store at -20°C.

CAS Number

934660-93-2

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