T100-Mut
T100-Mut is a cell-permeable peptide whose N-terminus is conjugated with a myristoylated group to enable T100-Mut to penetrate and localize to the inner side of the plasma membrane, thus mimicking the topology of Tmem100-3Q. T100-Mut can alleviate TRPA1-mediated pain[1].
Product Specifications
UNSPSC
12352209
Target
TRP Channel
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/t100-mut.html
Solubility
10 mM in DMSO
Smiles
CCCCCCCCCCCCCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)C)=O)CC1=CC=CC=C1)=O)CC(C)C)=O)CS)=O)CCCNC(N)=N)=O)CCC(N)=O)=O)CC(N)=O)=O)C(C)C)=O)C(C)C)=O)CC(C)C)=O)C)=O)[C@@H](C)O)=O)CCC(N)=O)=O)CO)=O)CCC(O)=O)=O)CCC(N)=O)=O)CCC(N)=O)=O)CCC(N)=O)=O)C(C)C)=O)CCCCN)=O)CCCCN)=O)CC(N)=O)=O)CCCNC(N)=N)=O)CCC(N)=O)=O)CCCNC(N)=N)=O)C(C)C)=O)CCCCN)=O)CC2=CNC3=CC=CC=C23)=O
Molecular Formula
C161H271N49O42S
Molecular Weight
3597.30
References & Citations
[1]Weng HJ, et al. Tmem100 Is a Regulator of TRPA1-TRPV1 Complex and Contributes to Persistent Pain. Neuron. 2015 Feb 18;85 (4) :833-46.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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