Lonapalene

Lonapalene (RS4317) is a topically effective 5-lipoxygenase (5-LO) inhibitor.

Product Specifications

CAS Number

[91431-42-4]

Product Name Alternative

RS4317

UNSPSC

12352005

Target

Lipoxygenase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/RS4317.html

Concentration

10mM

Purity

99.45

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

COC1=C(OC)C(OC(C)=O)=C2C=CC(Cl)=CC2=C1OC(C)=O

Molecular Formula

C16H15ClO6

Molecular Weight

338.74

References & Citations

[1]Black AK, et al. Pharmacologic and clinical effects of lonapalene (RS 43179), a 5-lipoxygenase inhibitor, in psoriasis. J Invest Dermatol. 1990 Jul;95 (1) :50-4.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 2

Isoform

5-LOX

Available Sizes

Curated Selection

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