Human ASMT Protein

<strong>Human ASMT Protein</strong>_x000D_ <strong>Catalog number:</strong> B2011793_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 1 mg/mL_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> HIOMTY protein, Acetylserotonin O-methyltransferase protein, HIOMT protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Botros HG, Legrand P, Pagan C, Bondet V, Weber P, Ben-Abdallah M, Lemière N, Huguet G, Bellalou J, Maronde E, Beguin P, Haouz A, Shepard W, Bourgeron T. Crystal structure and functional mapping of human ASMT, the last enzyme of the melatonin synthesis pathway J Pineal Res. 2013 Jan;54(1):46-57._x000D_ 2: Talarowska M, Szemraj J, Zajączkowska M, Gałecki P. ASMT gene expression correlates with cognitive impairment in patients with recurrent depressive disorder Med Sci Monit. 2014 Jun 2;20:905-12._x000D_ 3: Tran QH, Than VT, Luu PL, Clarke D, Lam HN, Nguyen TT, Nguyen DT, Duy PQ, Phung D, Nguyen MN. A novel signature predicts recurrence risk and therapeutic response in breast cancer patients Int J Cancer. 2021 Jun 1;148(11):2848-2856._x000D_ 4: Pagan C, Botros HG, Poirier K, Dumaine A, Jamain S, Moreno S, de Brouwer A, Van Esch H, Delorme R, Launay JM, Tzschach A, Kalscheuer V, Lacombe D, Briault S, Laumonnier F, Raynaud M, van Bon BW, Willemsen MH, Leboyer M, Chelly J, Bourgeron T. Mutation screening of ASMT, the last enzyme of the melatonin pathway, in a large sample of patients with intellectual disability BMC Med Genet. 2011 Jan 20;12:17._x000D_ 5: Wang L, Li J, Ruan Y, Lu T, Liu C, Jia M, Yue W, Liu J, Bourgeron T, Zhang D. Sequencing ASMT identifies rare mutations in Chinese Han patients with autism PLoS One. 2013;8(1):e53727._x000D_ 6: Rath MF, Coon SL, Amaral FG, Weller JL, Møller M, Klein DC. Melatonin Synthesis: Acetylserotonin O-Methyltransferase (ASMT) Is Strongly Expressed in a Subpopulation of Pinealocytes in the Male Rat Pineal Gland Endocrinology. 2016 May;157(5):2028-40._x000D_ 7: Zhang K, Ruan Z, Li J, Bian C, You X, Coon SL, Shi Q. A Comparative Genomic and Transcriptomic Survey Provides Novel Insights into N-Acetylserotonin Methyltransferase (ASMT) in Fish Molecules. 2017 Oct 2;22(10):1653._x000D_ 8: Maronde E, Saade A, Ackermann K, Goubran-Botros H, Pagan C, Bux R, Bourgeron T, Dehghani F, Stehle JH. Dynamics in enzymatic protein complexes offer a novel principle for the regulation of melatonin synthesis in the human pineal gland J Pineal Res. 2011 Aug;51(1):145-55._x000D_ 9: Moskaleva PV, Shnayder NA, Nasyrova RF. [Association of polymorphic variants of DDC (AADC), AANAT and ASMT genes encoding enzymes for melatonin synthesis with the higher risk of neuropsychiatric disorders] Zh Nevrol Psikhiatr Im S S Korsakova. 2021;121(5):151-157._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/20377855">10: Jonsson L, Ljunggren E, Bremer A, Pedersen C, Landén M, Thuresson K, Giacobini M, Melke J. Mutation screening of melatonin-related genes in patients with autism spectrum disorders BMC Med Genomics. 2010 Apr 8;3:10. </a>_x000D_ _x000D_ <strong>Products Related to Human ASMT Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>