8-Azaguanosine
8-Azaguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
[2133-80-4]
UNSPSC
12352005
Hazard Statement
H315-H319
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/8-azaguanosine.html
Solubility
10 mM in DMSO
Smiles
O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C(N=C(N)NC3=O)=C3N=N2
Molecular Formula
C9H12N6O5
Molecular Weight
284.23
Precautions
P264-P280-P302+P352-P305+P351+P338-P362+P364
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
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