Benzoin
Benzoin (DL-Benzoin), a natural balsamic resin, is a PI3Kα inhibitor with anticancer effects. Benzoin inihits the growth of colon cancer cell line (HCT-116) . Benzoin can be used as a food additive[1][2].
Product Specifications
CAS Number
119-53-9
Product Name Alternative
DL-Benzoin; Desyl alcohol; (±) -2-Hydroxy-2-phenylacetophenone
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PI3K
Type
Natural Products
Related Pathways
PI3K/Akt/mTOR
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/benzoin.html
Purity
99.95
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
OC(C1=CC=CC=C1)C(C2=CC=CC=C2)=O
Molecular Formula
C14H12O2
Molecular Weight
212.25
Precautions
H302, H315, H319, H335
References & Citations
[1]John JW Coppen, et al. Benzoin: Production, Uses and International Trade. Apr 6th, 2016.|[2]Sabbah DA, et al. Molecular modeling based approach, synthesis, and cytotoxic activity of novel benzoin derivatives targeting phosphoinostide 3-kinase (PI3Kα) . Bioorg Med Chem Lett. 2015 Aug 15;25 (16) :3120-4.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Natural Products
Clinical Information
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