Protease-Activated Receptor-2, amide
Protease-Activated Receptor-2, amide (SLIGKV-NH2) is a highly potent protease-activated receptor-2 (PAR2) activating peptide.
Product Specifications
CAS Number
[190383-13-2]
UNSPSC
12352209
Hazard Statement
H302, H315, H319
Target
Protease Activated Receptor (PAR)
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Protease-Activated_Receptor-2,_amide.html
Purity
98.89
Solubility
|H2O : 33.33 mg/mL (ultrasonic)
Smiles
CC(C)[C@@H](C(N)=O)NC([C@H](CCCCN)NC(CNC([C@H]([C@@H](C)CC)NC([C@H](CC(C)C)NC([C@H](CO)N)=O)=O)=O)=O)=O
Molecular Formula
C28H54N8O7
Molecular Weight
614.78
Precautions
H302, H315, H319
References & Citations
[1]Kanke T, et al. Binding of a highly potent protease-activated receptor-2 (PAR2) activating peptide, [3H]2-furoyl-LIGRL-NH2, to human PAR2. Br J Pharmacol. 2005 May;145 (2) :255-63.|[2]Ramelli G, et al. Protease-activated receptor 2 signalling promotes dendritic cell antigen transport and T-cellactivation in vivo. Immunology. 2010 Jan;129 (1) :20-7.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
PAR2
Available Sizes
Curated Selection
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