NaV1.8 Rabbit Polyclonal Antibody
Tetrodotoxin-resistant channel that mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. Plays a role in neuropathic pain mechanisms.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
PN3, Scn10a, Sns
Swiss Prot
Q6QIY3 Mouse, Q62968 Rat
Cellular Locus
Plasma membrane.
Host
Rabbit
Species Reactivity
Mouse,Rat
Immunogen
Synthetic peptide within rat NaV18 aa 1,907-1,956 / 1,956.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
Rat spinal cord lysates, mouse brain tissue, mouse brain tissue lysates.
Concentration
1 mg/mL
Dilution
WB: 1:100-1:1,000 ;IHC-P: 1:50-1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 220 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No
Frequently Asked Questions
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