Sheng Gelieting

Sheng Gelieting (CGT-8012) is a dipeptidy peptidase-IV enzyme (DP-IV) inhibitor. Sheng Gelieting has great DP-IV inhibition activity with an IC50 value of 87 nM. Sheng Gelieting can be used for curing or preventing diseases relevant to the dipeptidy peptidase-IV enzyme, such as the diabetes, particularly the II-type diabete[1].

Product Specifications

CAS Number

[1152810-23-5]

Product Name Alternative

CGT-8012

UNSPSC

12352005

Target

Dipeptidyl Peptidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/sheng-gelieting.html

Purity

98.29

Solubility

10 mM in DMSO

Smiles

FC(F)(C1=NC=C2N1CCN(C(C[C@H](N)CC3=C(C=C(C(F)=C3)F)F)=O)C2)F

Molecular Formula

C17H16F6N4O

Molecular Weight

406.33

References & Citations

[1]Qiang Yu, et al. Beta-amino tetrahydropyrazine, tetrahydropyrimidine and tetrahydropyridine used as dipeptidy peptidase inhibitors for curing or preventing diabetes. Patent. CN101899047A.