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PDZK1 Mouse Monoclonal Antibody [Clone ID: LBI2B2]

Product Specifications

Background

This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

Synonyms

CAP70; CLAMP; NHERF-3; NHERF3; PDZD1

Gene Name

PDZ domain containing 1

Gene ID

5174

UniProt

Q5T2W1

Conjugation

Unconjugated

Concentration

1 mg/ml

Dilution

WB 1:500

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

PDZK1

Overview

PDZK1 mouse monoclonal antibody, clone LBI2B2

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=5174

Uniprot URL

https://www.uniprot.org/uniprot/Q5T2W1

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