AA863
AA863 is a 5-lipoxygenase inhibitor with activity in inhibiting the proliferation of human glioma cells. AA863 exhibits significant and dose-dependent inhibitory effects in monolayer cultured glioma cells with an IC50 of 9.0 micromolar[1].
Product Specifications
CAS Number
80809-95-6
UNSPSC
12352211
Target
Lipoxygenase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/aa863.html
Smiles
O=C1C(CCCCC#CCCCC#CCO)=C(C(C(OC)=C1OC)=O)C
Molecular Formula
C21H26O5
Molecular Weight
358.43
References & Citations
[1]Effects of the 5-lipoxygenase inhibitors AA-863 and U-60,257 on human glioma cell lines
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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