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Dihydrocephalomannine

Dihydrocephalomannine (compound 1b), an analogue of Paclitaxel, shows reduced cytotoxicity and tubulin binding compared to Paclitaxel[1].

Product Specifications

CAS Number

159001-25-9

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Microtubule/Tubulin

Type

Natural Products

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dihydrocephalomannine.html

Purity

98.04

Solubility

10 mM in DMSO

Smiles

CCC(C)C(N[C@@H](C1=CC=CC=C1)[C@H](C(O[C@H](C(C)=C2[C@H](C([C@@]3([C@H](C[C@@H]4[C@](CO4)(OC(C)=O)[C@@]53[H])O)C)=O)OC(C)=O)C[C@](C2(C)C)([C@H]5OC(C6=CC=CC=C6)=O)O)=O)O)=O

Molecular Formula

C45H55NO14

Molecular Weight

833.92

Precautions

H302, H315, H319, H335

References & Citations

[1]Paclitaxel Analogue

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Frequently Asked Questions

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