PU 23
PU 23 is a non-carboxylic multidrug resistance protein 4 (MRP4) inhibitor as an active agent reducing resistance to anticancer agent 6-Mercaptopurine[1].
Product Specifications
CAS Number
[817635-93-1]
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
P-glycoprotein
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pu-23.html
Purity
99.48
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(NC(NC1=CC=C(S(=O)(NCC2=CC=CC=C2)=O)C=C1)=S)C3=CC=CC=C3
Molecular Formula
C21H19N3O3S2
Molecular Weight
425.52
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Ya Chen, et al. Discovery of novel multidrug resistance protein 4 (MRP4) inhibitors as active agents reducing resistance to anticancer drug 6-Mercaptopurine (6-MP) by structure and ligand-based virtual screening. PLoS One. 2018 Oct 15;13 (10) :e0205175.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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