Dermcidin Protein, Human, Recombinant (hFc Tag)
Product Specifications
Background
Hepatocellular carcinoma (HCC) is a major contributor to cancer-related deaths due to its often late stage diagnosis, and dermcidin (DCD) may have the potential to be used as a serum biomarker for HCC for more timely diagnoses. Human dermcidin (DCD) is an antimicrobial peptide secreted constitutively by sweat glands. And the role of DCD in ischemic heart disease has drawn increasing attention in particular its relationship with insulin secretion and glycemic control, nitric oxide (NO) synthesis and hypertension, platelet aggregation and acute myocardial infarction (AMI) .
Synonyms
AIDD Protein, Human; DCD-1 Protein, Human; DSEP Protein, Human; HCAP Protein, Human; PIF Protein, Human
Gene Name
Dermcidin
Expression System
HEK293 Cells
Tag
N-hFc
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
Purity
> 95 % as determined by SDS-PAGE.
Activity
At Leading Biology, the biological activity of a recombinant protein is routinely measured using a bioassay, e.g. chemotaxis or cell proliferation assay, enzyme assay, or a functional ELISA. When a recombinant protein is an enzyme, specific activity is derived from an enzymatic assay. Each enzyme is tested for potency by cleavage of a substrate. We are in the process of updating the biological activity data. If you have any questions regarding this update, please feel free to contact our technical support team.
Form
Lyophilized
Buffer
Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Molecular Weight
The recombinant human DCD consists 307 amino acids and predicts a molecular mass of 33.1 kDa.
Storage Conditions
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Product Datasheet
http://www.leading-biology.com/en/fastadmin/public/data/datasheet/S_Protein_datasheet/PH51534M3.pdf
Symbol
DCD
Species
Human
Protein ID
NP_444513.1
Overview
A DNA sequence encoding the human DCD (NP_444513.1) (Ser63-Val109) was expressed with the Fc region of human IgG1 at the N-terminus.
AA Sequence
Ser63-Val109
Protein ID Link
https://www.ncbi.nlm.nih.gov/protein/NP_444513.1
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1345381-01 0.02 mg (E-Coli)
Recombinant Staphylococcus aureus N- (5'-phosphoribosyl)anthranilate isomerase (trpF)
Ask
View Details 
MBS1345381-02 0.1 mg (E-Coli)
Recombinant Staphylococcus aureus N- (5'-phosphoribosyl)anthranilate isomerase (trpF)
Ask
View Details 
MBS1345381-03 0.02 mg (Yeast)
Recombinant Staphylococcus aureus N- (5'-phosphoribosyl)anthranilate isomerase (trpF)
Ask
View Details MBS1345381-04 0.1 mg (Yeast)
Recombinant Staphylococcus aureus N- (5'-phosphoribosyl)anthranilate isomerase (trpF)
Ask
View Details 
MBS1345381-05 0.02 mg (Baculovirus)
Recombinant Staphylococcus aureus N- (5'-phosphoribosyl)anthranilate isomerase (trpF)
Ask
View Details MBS1345381-06 0.02 mg (Mammalian-Cell)
Recombinant Staphylococcus aureus N- (5'-phosphoribosyl)anthranilate isomerase (trpF)
Ask
View Details