Notrilobolide
Notrilobolide is a sesquiterpene lactone. Notrilobolide induces a potent histamine release from peritoneal rat mast cells[1].
Product Specifications
CAS Number
2363714-40-1
UNSPSC
12352005
Target
Histamine Receptor
Type
Natural Products
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/notrilobolide.html
Purity
88.55
Smiles
O[C@@]12[C@](OC([C@]2(O)C)=O)([H])C3=C(C)[C@H](OC(/C(C)=C/C)=O)CC3([H])[C@](C)(C[C@@H]1OC(CCC)=O)OC(C)=O
Molecular Formula
C26H36O10
Molecular Weight
508.56
References & Citations
[1]Smitt UW, et al. Nortrilobolide, a new potent guaianolide secretagogue from Thapsia garganica. Planta Med. 1991 Apr;57 (2) :196-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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