PE/Cyanine5 Anti-Mouse CD3 Antibody[17A2]
Product Specifications
Background
CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.
Abbreviation
CD3
Gene ID
12500;12501;12502;12503
UniProt
P04235; P11942; P22646; P24161
Host
Rat
Reactivity
Mouse
Target
CD3; CD3E/D/G/Z; CD3e/d/g/z; T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain
Clonality
Monoclonal
Clone
17A2
Conjugation
PE/Cyanine 5
Applications
FCM
Field of Research
Immunology
Concentration
5 μL/Test
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Citation 01
https://www.frontiersin.org/articles/10.3389/fphar.2024.1390170/full
Citation 02
https://www.mdpi.com/1999-4923/17/2/166
Recommended Usage
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype
Rat IgG2b, κ
Available Sizes
Documents
Frequently Asked Questions
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