Proparacaine (Hydrochloride)

Proparacaine Hydrochloride (Proxymetacaine Hydrochloride) is a derivative of lidocaine (HY-B0185), with immunomodulatory effect and glucocorticomimetic activity[1][2].

Product Specifications

CAS Number

[5875-06-9]

Product Name Alternative

Proxymetacaine Hydrochloride

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis

Type

Reference compound

Related Pathways

Apoptosis

Applications

Neuroscience-Neuromodulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Proparacaine-Hydrochloride.html

Purity

99.87

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : 33.33 mg/mL (ultrasonic)

Smiles

O=C(OCCN(CC)CC)C1=CC=C(OCCC)C(N)=C1.[H]Cl

Molecular Formula

C16H27ClN2O3

Molecular Weight

330.85

Precautions

H302, H315, H319, H335

References & Citations

[1]Wen Yi Fan, et al. Proparacaine induces cytotoxicity and mitochondria-dependent apoptosis in corneal stromal cells both in vitro and in vivo. Toxicol Res (Camb) . 2016 Sep 1; 5 (5) : 1434-1444.|[2]Hwan Soo Kim, et al. Effect of Proparacaine in a Mouse Model of Allergic Rhinitis. Clin Exp Otorhinolaryngol. 2017 Dec; 10 (4) : 325–331.