Pyruvic acid-13C2-1 (sodium)

2-Oxopropanoate-13C2 (sodium) is the 13C labeled Sodium 2-oxopropanoate[1]. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS[2][3].

Product Specifications

CAS Number

[89196-78-1]

Product Name Alternative

Sodium 2-oxopropanoate-13C2; Acetylformic acid-13C2-1 (sodium)

UNSPSC

12352211

Hazard Statement

H317, H319

Target

Endogenous Metabolite; Reactive Oxygen Species (ROS)

Type

Isotope-Labeled Compounds

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/2-oxopropanoate-13c2-sodium.html

Purity

99.0

Solubility

10 mM in DMSO

Smiles

[13CH3][13C](C(O[Na])=O)=O

Molecular Formula

C 13C2H3NaO3

Molecular Weight

112.03

Precautions

H317, H319

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]S Nemoto, et al. Role for mitochondrial oxidants as regulators of cellular metabolism. Mol Cell Biol. 2000 Oct;20 (19) :7311-8.|[3]W Zhao, et al. Fructose induced deactivation of antioxidant enzymes: preventive effect of pyruvate. Free Radic Res. 2000 Jul33 (1) :23-30.