Betulin-d3
Betulin-d3 (Trochol-d3) is deuterium labeled Betulin. Betulin (Trochol), is a sterol regulatory element-binding protein (SREBP) inhibitor with an IC50 of 14.5 μM in K562 cell line[1].
Product Specifications
Product Name Alternative
Trochol-d3
UNSPSC
12352211
Target
Apoptosis; Endogenous Metabolite; Fatty Acid Synthase (FASN) ; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis; Metabolic Enzyme/Protease; Others
Field of Research
Cancer
Smiles
CC1(C)[C@@]([2H])(O)C([2H])([2H])C[C@@]2(C)C1CC[C@]3(C)C2CCC4[C@@]3(C)CC[C@]5(CO)C4[C@H](C(C)=C)CC5
Molecular Formula
C30H47D3O2
Molecular Weight
445.74
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Król SK, et al. Comprehensive review on betulin as a potent anticancer agent. Biomed Res Int. 2015;2015:584189.|[3]Drag M, et al. Comparision of the Cytotoxic Effects of Birch Bark Extract, Betulin and Betulinic Acid Towards Human Gastric Carcinoma and Pancreatic Carcinoma Drug-sensitive and Drug-Resistant Cell Lines. Molecules. 2009 Apr 24;14 (4) :1639-51.|[4]Ma C, et al. Protective effect of betulin on cognitive decline in streptozotocin (STZ) -induced diabetic rats. Neurotoxicology. 2016 Dec;57:104-111.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Human IL-6 Recombinant Rabbit Monoclonal Antibody [PS00-21] - BSA and Azide free (Capture)](https://cdn.genprice.uk/products/992/68dd1c8b061270361ea8185e/imageurl/ha721167.webp)
HA721167 100 µL
Human IL-6 Recombinant Rabbit Monoclonal Antibody [PS00-21] - BSA and Azide free (Capture)
Sign In for Pricing
View Details 
PKSH034200-01 20 µg
Recombinant Human Interleukin-2/IL-2 Protein (active)
Sign In for Pricing
View Details PKSH034200-02 50 µg
Recombinant Human Interleukin-2/IL-2 Protein (active)
Sign In for Pricing
View Details 
