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Recombinant Human Interleukin-2/IL-2 Protein (active)

Product Specifications

Background

Interleukin-2 (IL-2) is an interleukin; a type of cytokine signaling molecule in the immune system; belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells; NK cells; lymphokine-activated killer cells; monocytes; macrophages and oligodendrocytes.

Abbreviation

Interleukin-2/IL-2

Synonyms

Interleukin-2; IL-2; T-Cell Growth Factor; TCGF; Aldesleukin

UniProt

P60568-1

Accession Number

P60568-1

Expression System

HEK293 cells

Tag

None

Sequence

Ala 21-Thr 153

Field of Research

Immunology

Endotoxin

≤0.01 EU per μg by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Human IL-2 Protein, Tag Free stimulates proliferation of CTLL-2 cells. The specific activity of Human IL-2 Protein, Tag Free is > 0.60 x 10^7 IU/mg, which is calibrated against human IL-2 WHO International Standard.

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

15.4 kDa

Observed Molecular Weight

14-22 kDa

Formulation

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Species

Human

Available Sizes

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