Dermorphin
Dermorphin is a natural heptapeptide μ-opioid receptor (MOR) agonist found in amphibian skin. Inhibition of neuropathic pain[1].
Product Specifications
CAS Number
77614-16-5
UNSPSC
12352209
Target
Opioid Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Dermorphin.html
Purity
99.10
Solubility
H2O : ≥ 100 mg/mL
Smiles
OC(C=C1)=CC=C1C[C@H](NC(CNC([C@@H](NC([C@@H](C)NC([C@@H](N)CC2=CC=C(O)C=C2)=O)=O)CC3=CC=CC=C3)=O)=O)C(N4[C@@H](CCC4)C(N[C@@H](CO)C(N)=O)=O)=O
Molecular Formula
C40H50N8O10
Molecular Weight
802.87
References & Citations
[1]Tiwari V, et al. Activation of Peripheral μ-opioid Receptors by Dermorphin [D-Arg2, Lys4] (1-4) Amide Leads to Modality-preferred Inhibition of Neuropathic Pain. Anesthesiology. 2016 Mar;124 (3) :706-20.|[2]Bird MF, et al. Characterisation of the Novel Mixed Mu-NOP Peptide Ligand Dermorphin-N/OFQ (DeNo) . PLoS One. 2016 Jun 7;11 (6) :e0156897.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
μ Opioid Receptor/MOR
Available Sizes
Frequently Asked Questions
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