Aucuparin
Aucuparin, a natural product found in Sorbus aucuparia, inhibits pulmonary fibrosis in a bleomycin -induced lung fibrosis mouse model. Aucuparin has anti-inflammatory activity and can inhibit the activation of inflammatory factors by TGF-β[1].
Product Specifications
CAS Number
3687-28-3
UNSPSC
12352005
Target
TGF-beta/Smad
Type
Reference compound
Related Pathways
Stem Cell/Wnt; TGF-beta/Smad
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/aucuparin.html
Solubility
10 mM in DMSO
Smiles
OC1=C(OC)C=C(C=C1OC)C2=CC=CC=C2
Molecular Formula
C14H14O3
Molecular Weight
230.26
References & Citations
[1]Lee SY, et al. Aucuparin Suppresses Bleomycin-Induced Pulmonary Fibrosis Via Anti-Inflammatory Activity. J Med Food. 2021;24 (2) :151-160.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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