Ecopipam (hydrochloride)
Ecopipam (SCH 39166) hydrochloride is a potent, selective and orally active antagonist of dopamine D1/D5 receptor, with Kis of 1.2 nM and 2.0 nM, respectively. Ecopipam hydrochloride shows more than 40-flod selectivity over D2, D4, 5-HT, and α2a receptor (Ki=0.98, 5.52, 0.08, and 0.73 μM, respectively) . Ecopipam hydrochloride can be used for the research of schizophrenia and obesity[1][3].
Product Specifications
CAS Number
190133-94-9
Product Name Alternative
SCH 39166 (hydrochloride)
UNSPSC
12352005
Hazard Statement
H302
Target
5-HT Receptor; Adrenergic Receptor; Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ecopipam-hydrochloride.html
Purity
99.19
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1=C(Cl)C=C2C([C@]3([H])[C@@](CCC4=C3C=CC=C4)([H])N(C)CC2)=C1.[H]Cl
Molecular Formula
C19H21Cl2NO
Molecular Weight
350.28
Precautions
H302
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Isoform
D1 Receptor; D2 Receptor; D4 Receptor; D5 Receptor; MUC4; α adrenergic receptor
Available Sizes
Frequently Asked Questions
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