PCSK9, Mouse (HEK293, His)
The PCSK9 protein regulates cholesterol levels by degrading LDLR, VLDLR, LRP1/APOER, and LRP8/APOER2 receptors. It promotes LDLR degradation, inhibits recycling, induces ubiquitination, and affects APOB degradation. Additionally, PCSK9 influences BACE1 intermediates, ENaC surface expression, and neuronal apoptosis by modulating LRP8/APOER2 levels and anti-apoptotic signaling pathways. PCSK9 Protein, Mouse (HEK293, His) is the recombinant mouse-derived PCSK9 protein, expressed by HEK293, with C-6*His labeled tag.
Product Specifications
Product Name Alternative
PCSK9 Protein, Mouse (HEK293, His), Mouse, HEK293
UNSPSC
12352202
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/pcsk9-protein-mouse-660a-a-hek293-c-his.html
Purity
98.0
Smiles
Molecular Formula
100102 (Gene_ID) Q80W65 (Q35-Q155&S156-Q694) (Accession)
Molecular Weight
19.37 & 55 kDa
Shipping Conditions
Room temperature in continental US; may vary elsewhere.
Storage Conditions
Stored at -20°C for 2 years
Scientific Category
Recombinant Proteins
Available Sizes
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