RasGRP3 ligand 1

RasGRP3 ligand 1 (compound 96) is a RasGRP3 ligand with a Ki of 1.75 nM. RasGRP3 ligand 1 can induce Ras activation and can be used for cancer research[1].

Product Specifications

CAS Number

[2229068-13-5]

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

Ras

Type

Reference compound

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/rasgrp3-ligand-1.html

Solubility

10 mM in DMSO

Smiles

CN1C2=CC=CC=C2C(/C=C3CC(CO)(OC\3=O)COC(C(C)(C)C)=O)=C1

Molecular Formula

C21H25NO5

Molecular Weight

371.43

Precautions

P264-P270-P280-P302+P352-P330-P362+P364-P501

References & Citations

[1]Ann J, et al. α-Arylidene Diacylglycerol-Lactones (DAG-Lactones) as Selective Ras Guanine-Releasing Protein 3 (RasGRP3) Ligands. J Med Chem. 2018 Jul 26;61 (14) :6261-6276.