13,14-Dihydro-15-keto-PGE1

13,14-Dihydro-15-keto-PGE1 is an inactive metabolite of PGE1. 13, 14-Dihydro-15-Keto-pGE1 inhibited platelet aggregation in ADP-induced human isolated platelet-rich plasma with IC50 14.8 μg/mL[1].

Product Specifications

CAS Number

[5094-14-4]

UNSPSC

12352211

Target

Drug Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/13-14-dihydro-15-keto-pge1.html

Solubility

10 mM in DMSO

Smiles

OC(CCCCCC[C@@H]1[C@H]([C@@H](CC1=O)O)CCC(CCCCC)=O)=O

Molecular Formula

C20H34O5

Molecular Weight

354.48

References & Citations

[1]Katzenschlager R, et al. Synergism between PGE1-metabolites (13,14-dihydro-prostaglandin E1, 15-keto prostaglandin E1, 15-keto-13,14-dihydro-prostaglandin E1) and nitric oxide (NO) on platelet aggregation. Prostaglandins Leukot Essent Fatty Acids. 1992 Mar;45 (3) :207-10.