VPS24 Recombinant Rabbit Monoclonal Antibody [JE34-58]
Charged multivesicular body protein 3 is a protein that in humans is encoded by the VPS24 gene. This gene encodes a protein that acts in the sorting of transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily. Alternative splicing results in multiple transcript variants encoding different isoforms.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
CHMP3, CGI149, NEDF, VPS24, CGI-149
Swiss Prot
Q9Y3E7 Human, Q9CQ10 Mouse, Q8CGS4 Rat
Cellular Locus
Cytoplasm, cytosol, Membrane, Endosome, Late endosome membrane.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within
Isotype
IgG
Clone
JE34-58
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB
Positive Control
HepG2 cell lysate, U-87 MG cell lysate, Human brain tissue lysate, Mouse brain tissue lysate, Rat brain tissue lysate.
Concentration
1 mg/mL
Dilution
WB: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 29 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
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