(E/Z) -Piperine

(E/Z) -Piperine ((E/Z) -Bioperine) is an alkaloid with a pungent property. (E/Z) -Piperine shows anti-inflammation, immunomodulatory and anti-cancer, antispasmodic and anti-secretory effects. (E/Z) -Piperine demonstrates significant neuroprotective effect in Alzheimer’s disease and Parkinson’s disease[1].

Product Specifications

CAS Number

[7780-20-3]

Product Name Alternative

(E/Z) -Bioperine; (E/Z) -1-Piperoylpiperidine

UNSPSC

12352005

Hazard Statement

H302

Target

Cytochrome P450; P-glycoprotein

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/e-z-piperine.html

Purity

98.91

Solubility

10 mM in DMSO

Smiles

O=C(N1CCCCC1)/C=C/C=C/C2=CC=C(OCO3)C3=C2

Molecular Formula

C17H19NO3

Molecular Weight

285.34

Precautions

H302

References & Citations

[1]Chenrui Li, et al. Non-linear pharmacokinetics of piperine and its herb-drug interactions with docetaxel in Sprague-Dawley rats. J Pharm Biomed Anal. 2016 Sep 5:128:286-293.