AHR-1911
Product Specifications
UNSPSC Description
AHR-1911 (10-Undecen-1-yl-Thiopseudourea Iodide;Isothiuronium) is a thiourea-based anti-inflammatory and anti-tumor agent that has an improving effect on burned skin. AHR-1911 produces histamine-like effects when injected intradermally and may reduce arterial pressure in anesthetized dogs. AHR-1911 inhibits tumor growth and reduces microsomal and C-polysome protein synthesis[1][2].
Target Antigen
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
cancer
Assay Protocol
https://www.medchemexpress.com/ahr-1911.html
Purity
99.66
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
C=CCCCCCCCCCSC(N)=N.[H]I
Molecular Weight
356.31
References & Citations
[1]Fuenmayor L, et al. Effect of 10 undecen 1-YL thiopseudourea iodide (AHR-1911) on rat arterial pressure and capillary permeability. Proc Soc Exp Biol Med. 1973 Jun;143(2):568-71.|[2]González-Cadavid NF, et al. Inhibition of translation in liver polyribosomes by a new substituted thiopseudourea with antitumour action. Biochem J. 1974 Feb;138(2):129-41.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-107063/AHR-1911-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-107063/
Clinical Information
No Development Reported
CAS Number
22584-04-9
Available Sizes
Curated Selection
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