AHR-1911

AHR-1911 (10-Undecen-1-yl-Thiopseudourea Iodide; Isothiuronium) is a thiourea-based anti-inflammatory and anti-tumor agent that has an improving effect on burned skin. AHR-1911 produces histamine-like effects when injected intradermally and may reduce arterial pressure in anesthetized dogs. AHR-1911 inhibits tumor growth and reduces microsomal and C-polysome protein synthesis[1][2].

Product Specifications

CAS Number

[22584-04-9]

Product Name Alternative

10-Undecen-1-yl-thiopseudourea (iodide)

UNSPSC

12352211

Target

Histamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ahr-1911.html

Purity

99.66

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

C=CCCCCCCCCCSC(N)=N.[H]I

Molecular Formula

C12H25IN2S

Molecular Weight

356.31

References & Citations

[1]Fuenmayor L, et al. Effect of 10 undecen 1-YL thiopseudourea iodide (AHR-1911) on rat arterial pressure and capillary permeability. Proc Soc Exp Biol Med. 1973 Jun;143 (2) :568-71.|[2]González-Cadavid NF, et al. Inhibition of translation in liver polyribosomes by a new substituted thiopseudourea with antitumour action. Biochem J. 1974 Feb;138 (2) :129-41.